Needle-free injection of 5-aminolevulinic acid in photodynamic therapy for the treatment of condylomata acuminata
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چکیده
منابع مشابه
Needle-free injection of 5-aminolevulinic acid in photodynamic therapy for the treatment of condylomata acuminata
The external application of 5-aminolevulinic acid (ALA) in photodynamic therapy (PDT) results in a shallow penetration depth in thick or extensive condylomata acuminata (CA) lesions, thus demonstrating a poor therapeutic effect for those patients. To compare the efficacy of needle-free injection with external application of ALA in PDT for the treatment of CA, 160 CA patients with thick or exten...
متن کاملEvaluation of photodynamic therapy using topical aminolevulinic acid hydrochloride in the treatment of condylomata acuminate.
OBJECTIVES To investigate the efficacy and safety of topical application of 5-aminolaevulinic acid (ALA) photodynamic therapy (PDT) for the treatment of condylomata acuminata (CA) in larger population. METHODS Patients with CA were given a treatment of ALA-PDT once a week for 3 weeks and followed up at 4, 8, 12 and 24 weeks after the treatment finished. RESULTS In 531 patients, a clearance ...
متن کاملEffect of Silver Nanoparticles on Improving the Efficacy of 5-Aminolevulinic Acid-Induced Photodynamic Therapy
Introduction: The most important limitation of 5-aminolevulinic acid (5-ALA)-induced photodynamic therapy (PDT) is the efficacy of the cells in converting 5-ALA to protoporphyrin IX. The present study aimed to investigate the effectiveness of silver nanoparticles (AgNPs) with the photosensitivity at the surface plasmon resonance wavelength on 5-ALA-mediated PDT. Material and Methods: First of a...
متن کاملDerivatives of 5-Aminolevulinic Acid for Photodynamic Therapy
Photodynamic therapy (PDT) is a clinical treatment that combines the effects of visible light irradiation with subsequent biochemical events that arise from the presence of a photosensitising drug (possessing no dark toxicity) to cause destruction of selected cells. Today, the most common agent used in dermatological PDT is 5-aminolevulinic acid (ALA). As a result of its hydrophilic character, ...
متن کاملPhotodynamic therapy for acne vulgaris with topical 5-aminolevulinic acid.
After obtaining informed consent, the patient was treated with topical 5-aminolevulinic acid photodynamic therapy (ALA-PDT). Twenty percent ALA (A 7793; Sigma, St Louis, Mo) in an oil-in-water emulsion (Yoshida, Tokyo, Japan) was applied to a 5 3 5-cm area of the right cheek for 4 hours with a light-shielded dressing. On Wood lamp examination, the affected lesion showed numerous dots of vivid r...
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ژورنال
عنوان ژورنال: Experimental and Therapeutic Medicine
سال: 2013
ISSN: 1792-0981,1792-1015
DOI: 10.3892/etm.2013.1092